A mysterious virus emerges after a meteor lands near a remote village in Peru. Authorities brought in to investigate discover the horrific virus not only kills, but it reanimates its victims, turning them into the walking dead.

In spite of the government believing they have contained the outbreak, samples of the contagion are brought to the United States via infected military and other victims. The virus breaks boundaries and the infection spreads initiating the ground invasion of the War against the Undead.